Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia

A new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids – N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine – were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, co...

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Detalles Bibliográficos
Autores principales: Sulaiman, Syazreen Nadia, Mukhtar, Mat Ropi, Hadi, A Hamid A, Awang, Khalijah, Hazni, Hazrina, Zahari, Azeana, Litaudon, Marc, Zaima, Kazumasa, Morita, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260609/
https://www.ncbi.nlm.nih.gov/pubmed/21490559
http://dx.doi.org/10.3390/molecules16043119
Descripción
Sumario:A new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids – N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine – were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, complete (13)C-NMR data of N-allyl-laurolitsine (2) was also reported. The alkaloidal structures were elucidated by means of high field 1D- and 2D-NMR IR, UV, and LCMS-IT-TOF spectral data. N-Allyllaurolitsine (2) showed a moderate vasorelaxant activity on isolated rat aorta.

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