Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia

A new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids – N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine – were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, co...

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Autores principales: Sulaiman, Syazreen Nadia, Mukhtar, Mat Ropi, Hadi, A Hamid A, Awang, Khalijah, Hazni, Hazrina, Zahari, Azeana, Litaudon, Marc, Zaima, Kazumasa, Morita, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260609/
https://www.ncbi.nlm.nih.gov/pubmed/21490559
http://dx.doi.org/10.3390/molecules16043119
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author Sulaiman, Syazreen Nadia
Mukhtar, Mat Ropi
Hadi, A Hamid A
Awang, Khalijah
Hazni, Hazrina
Zahari, Azeana
Litaudon, Marc
Zaima, Kazumasa
Morita, Hiroshi
author_facet Sulaiman, Syazreen Nadia
Mukhtar, Mat Ropi
Hadi, A Hamid A
Awang, Khalijah
Hazni, Hazrina
Zahari, Azeana
Litaudon, Marc
Zaima, Kazumasa
Morita, Hiroshi
author_sort Sulaiman, Syazreen Nadia
collection PubMed
description A new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids – N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine – were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, complete (13)C-NMR data of N-allyl-laurolitsine (2) was also reported. The alkaloidal structures were elucidated by means of high field 1D- and 2D-NMR IR, UV, and LCMS-IT-TOF spectral data. N-Allyllaurolitsine (2) showed a moderate vasorelaxant activity on isolated rat aorta.
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spelling pubmed-62606092018-12-10 Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia Sulaiman, Syazreen Nadia Mukhtar, Mat Ropi Hadi, A Hamid A Awang, Khalijah Hazni, Hazrina Zahari, Azeana Litaudon, Marc Zaima, Kazumasa Morita, Hiroshi Molecules Article A new bisbenzylisoquinoline, lancifoliaine (1), together with seven known alkaloids – N-allyllaurolitsine (2), reticuline (3), actinodaphnine, norboldine, pallidine, cassythicine and boldine – were isolated from the stem bark of Litsea lancifolia (Lauraceae). In addition to that of lancifoliaine, complete (13)C-NMR data of N-allyl-laurolitsine (2) was also reported. The alkaloidal structures were elucidated by means of high field 1D- and 2D-NMR IR, UV, and LCMS-IT-TOF spectral data. N-Allyllaurolitsine (2) showed a moderate vasorelaxant activity on isolated rat aorta. MDPI 2011-04-13 /pmc/articles/PMC6260609/ /pubmed/21490559 http://dx.doi.org/10.3390/molecules16043119 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Sulaiman, Syazreen Nadia
Mukhtar, Mat Ropi
Hadi, A Hamid A
Awang, Khalijah
Hazni, Hazrina
Zahari, Azeana
Litaudon, Marc
Zaima, Kazumasa
Morita, Hiroshi
Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia
title Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia
title_full Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia
title_fullStr Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia
title_full_unstemmed Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia
title_short Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia
title_sort lancifoliaine, a new bisbenzylisoquinoline from the bark of litsea lancifolia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260609/
https://www.ncbi.nlm.nih.gov/pubmed/21490559
http://dx.doi.org/10.3390/molecules16043119
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