Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents

Propylene carbonate is shown to be an environmentally friendly and sustainable replacement for dichloromethane and acetonitrile in proline-catalysed α-hydrazinations of aldehydes and ketones. Enantioselectivities comparable to those obtained in conventional solvents or ionic liquids can be obtained,...

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Detalles Bibliográficos
Autores principales: Beattie, Christopher, North, Michael, Villuendas, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260617/
https://www.ncbi.nlm.nih.gov/pubmed/21512450
http://dx.doi.org/10.3390/molecules16043420
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author Beattie, Christopher
North, Michael
Villuendas, Pedro
author_facet Beattie, Christopher
North, Michael
Villuendas, Pedro
author_sort Beattie, Christopher
collection PubMed
description Propylene carbonate is shown to be an environmentally friendly and sustainable replacement for dichloromethane and acetonitrile in proline-catalysed α-hydrazinations of aldehydes and ketones. Enantioselectivities comparable to those obtained in conventional solvents or ionic liquids can be obtained, even when using a lower catalyst loading.
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spelling pubmed-62606172018-12-10 Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents Beattie, Christopher North, Michael Villuendas, Pedro Molecules Article Propylene carbonate is shown to be an environmentally friendly and sustainable replacement for dichloromethane and acetonitrile in proline-catalysed α-hydrazinations of aldehydes and ketones. Enantioselectivities comparable to those obtained in conventional solvents or ionic liquids can be obtained, even when using a lower catalyst loading. MDPI 2011-04-21 /pmc/articles/PMC6260617/ /pubmed/21512450 http://dx.doi.org/10.3390/molecules16043420 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Beattie, Christopher
North, Michael
Villuendas, Pedro
Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents
title Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents
title_full Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents
title_fullStr Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents
title_full_unstemmed Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents
title_short Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents
title_sort proline-catalysed amination reactions in cyclic carbonate solvents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260617/
https://www.ncbi.nlm.nih.gov/pubmed/21512450
http://dx.doi.org/10.3390/molecules16043420
work_keys_str_mv AT beattiechristopher prolinecatalysedaminationreactionsincycliccarbonatesolvents
AT northmichael prolinecatalysedaminationreactionsincycliccarbonatesolvents
AT villuendaspedro prolinecatalysedaminationreactionsincycliccarbonatesolvents

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