Simple and Efficient Synthesis of Racemic 2-(tert-Butoxycarbon-ylamino)-2-methyl-3-(1H-1,2,4-triazol-1-yl)propanoic Acid, a New Derivative of β-(1,2,4-Triazol-1-yl)alanine

A simple synthetic approach to racemic N-tert-butyloxycarbonyl-2-methyl-3-(1H-1,2,4-triazol-1-yl)alanine (5) in four steps and 68% overall yield starting from oxazoline derivative 1 is reported. This synthesis involves the alkylation of 1H-1,2,4-triazole with an O-tosyloxazoline derivative, followed...

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Detalles Bibliográficos
Autores principales: Aouine, Younas, Faraj, Hassane, Alami, Anouar, El-Hallaoui, Abdelilah, Elachqar, Abdelrhani, Kerbal, Abdelali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260622/
https://www.ncbi.nlm.nih.gov/pubmed/21512446
http://dx.doi.org/10.3390/molecules16043380

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