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Kazinol Q from Broussonetia kazinoki Enhances Cell Death Induced by Cu(ll) through Increased Reactive Oxygen Species

The ability of the flavan kazinol Q (KQ) to induce DNA breakage in the presence of Cu(II) was examined by agarose gel electrophoresis using supercoiled plasmid DNA. In KQ-mediated DNA breakage reaction, the involvement of reactive oxygen species (ROS), H(2)O(2) and O(2)(-) was established by the inh...

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Detalles Bibliográficos
Autores principales: Wei, Bai-Luh, Chen, Ying-Chieh, Hsu, Hsue-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260624/
https://www.ncbi.nlm.nih.gov/pubmed/21499221
http://dx.doi.org/10.3390/molecules16043212

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