Catalytic Enantioselective Aryl Transfer to Aldehydes Using Chiral 2,2’-Bispyrrolidine-Based Salan Ligands

Chiral C(2)-symmetric diamines have emerged as versatile auxiliaries or ligands in numerous asymmetric transformations. Chiral 2,2’-bispyrrolidine-based salan ligands were prepared and applied to the asymmetric aryl transfer to aldehydes with arylboronic acids as the source of transferable aryl grou...

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Detalles Bibliográficos
Autores principales: Jia, Xuefeng, Lin, Aijun, Mao, Zhijie, Zhu, Chengjian, Cheng, Yixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260645/
https://www.ncbi.nlm.nih.gov/pubmed/21471936
http://dx.doi.org/10.3390/molecules16042971
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author Jia, Xuefeng
Lin, Aijun
Mao, Zhijie
Zhu, Chengjian
Cheng, Yixiang
author_facet Jia, Xuefeng
Lin, Aijun
Mao, Zhijie
Zhu, Chengjian
Cheng, Yixiang
author_sort Jia, Xuefeng
collection PubMed
description Chiral C(2)-symmetric diamines have emerged as versatile auxiliaries or ligands in numerous asymmetric transformations. Chiral 2,2’-bispyrrolidine-based salan ligands were prepared and applied to the asymmetric aryl transfer to aldehydes with arylboronic acids as the source of transferable aryl groups. The corresponding diarylmethanols were obtained in high yields with moderate to good enantioselectivitives of up to 83% ee.
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spelling pubmed-62606452018-12-10 Catalytic Enantioselective Aryl Transfer to Aldehydes Using Chiral 2,2’-Bispyrrolidine-Based Salan Ligands Jia, Xuefeng Lin, Aijun Mao, Zhijie Zhu, Chengjian Cheng, Yixiang Molecules Article Chiral C(2)-symmetric diamines have emerged as versatile auxiliaries or ligands in numerous asymmetric transformations. Chiral 2,2’-bispyrrolidine-based salan ligands were prepared and applied to the asymmetric aryl transfer to aldehydes with arylboronic acids as the source of transferable aryl groups. The corresponding diarylmethanols were obtained in high yields with moderate to good enantioselectivitives of up to 83% ee. MDPI 2011-04-06 /pmc/articles/PMC6260645/ /pubmed/21471936 http://dx.doi.org/10.3390/molecules16042971 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Jia, Xuefeng
Lin, Aijun
Mao, Zhijie
Zhu, Chengjian
Cheng, Yixiang
Catalytic Enantioselective Aryl Transfer to Aldehydes Using Chiral 2,2’-Bispyrrolidine-Based Salan Ligands
title Catalytic Enantioselective Aryl Transfer to Aldehydes Using Chiral 2,2’-Bispyrrolidine-Based Salan Ligands
title_full Catalytic Enantioselective Aryl Transfer to Aldehydes Using Chiral 2,2’-Bispyrrolidine-Based Salan Ligands
title_fullStr Catalytic Enantioselective Aryl Transfer to Aldehydes Using Chiral 2,2’-Bispyrrolidine-Based Salan Ligands
title_full_unstemmed Catalytic Enantioselective Aryl Transfer to Aldehydes Using Chiral 2,2’-Bispyrrolidine-Based Salan Ligands
title_short Catalytic Enantioselective Aryl Transfer to Aldehydes Using Chiral 2,2’-Bispyrrolidine-Based Salan Ligands
title_sort catalytic enantioselective aryl transfer to aldehydes using chiral 2,2’-bispyrrolidine-based salan ligands
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260645/
https://www.ncbi.nlm.nih.gov/pubmed/21471936
http://dx.doi.org/10.3390/molecules16042971
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