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Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis
OBJECTIVE: This study was designed to verify the association between dementia and mortality in the elderly undergoing hip fracture surgery, and assessed the mortality of patients with dementia after hip fracture surgery. MATERIAL AND METHODS: PubMed, Embase, and Web of Science were searched until Ap...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260652/ https://www.ncbi.nlm.nih.gov/pubmed/30470251 http://dx.doi.org/10.1186/s13018-018-0988-6 |
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author | Bai, Jianzhong Zhang, Pei Liang, Xinyu Wu, Zhipeng Wang, Jingcheng Liang, Yuan |
author_facet | Bai, Jianzhong Zhang, Pei Liang, Xinyu Wu, Zhipeng Wang, Jingcheng Liang, Yuan |
author_sort | Bai, Jianzhong |
collection | PubMed |
description | OBJECTIVE: This study was designed to verify the association between dementia and mortality in the elderly undergoing hip fracture surgery, and assessed the mortality of patients with dementia after hip fracture surgery. MATERIAL AND METHODS: PubMed, Embase, and Web of Science were searched until April, 2018 without language restrictions. Two reviewers selected related studies, assessed study quality, and extracted data independently. Risk ratios (RRs) with 95% confidence intervals (CI) were derived using random-effects model throughout all analyses. The endpoints included 30-day, 6-month, 1-year, and more than 1-year mortality. This meta-analysis was performed following PRISMA statement and carried out by using stata14.0 software. RESULTS: Dementia significantly increased postoperative mortality of patients suffered from hip fracture in 30-day [RR = 1.57, 95% CI (1.29, 1.90), P<0.00], 6-month [RR = 1.97, 95% CI (1.47, 2.63), P<0.00], 1-year [RR = 1.77, 95% CI (1.54, 2.04), P<0.00], and more than 1-year follow up [RR = 1.60, 95% CI (1.30, 1.96), P<0.00] respectively. The mortality of dementia patients after hip fracture surgery in 30-day [ES = 12%, 95% CI (8%, 15%)], 6-month [ES = 32%, 95% CI (17%, 48%)], 1-year [ES = 39%, 95% CI (35%, 43%)], and more than 1-year follow up [ES = 45%, 95% CI (32%, 58%)]. CONCLUSIONS: Our meta-analysis demonstrated that the mortality of patients with dementia suffered from hip fracture surgery is 12%, 32%, 39%, and 45%, and dementia increased 1.57, 1.97, 1.77, and 1.60-fold mortality in patients undergoing hip fracture surgery in 30-day, 6-month, 1-year, and more than 1-year follow up respectively. |
format | Online Article Text |
id | pubmed-6260652 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-62606522018-11-30 Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis Bai, Jianzhong Zhang, Pei Liang, Xinyu Wu, Zhipeng Wang, Jingcheng Liang, Yuan J Orthop Surg Res Research Article OBJECTIVE: This study was designed to verify the association between dementia and mortality in the elderly undergoing hip fracture surgery, and assessed the mortality of patients with dementia after hip fracture surgery. MATERIAL AND METHODS: PubMed, Embase, and Web of Science were searched until April, 2018 without language restrictions. Two reviewers selected related studies, assessed study quality, and extracted data independently. Risk ratios (RRs) with 95% confidence intervals (CI) were derived using random-effects model throughout all analyses. The endpoints included 30-day, 6-month, 1-year, and more than 1-year mortality. This meta-analysis was performed following PRISMA statement and carried out by using stata14.0 software. RESULTS: Dementia significantly increased postoperative mortality of patients suffered from hip fracture in 30-day [RR = 1.57, 95% CI (1.29, 1.90), P<0.00], 6-month [RR = 1.97, 95% CI (1.47, 2.63), P<0.00], 1-year [RR = 1.77, 95% CI (1.54, 2.04), P<0.00], and more than 1-year follow up [RR = 1.60, 95% CI (1.30, 1.96), P<0.00] respectively. The mortality of dementia patients after hip fracture surgery in 30-day [ES = 12%, 95% CI (8%, 15%)], 6-month [ES = 32%, 95% CI (17%, 48%)], 1-year [ES = 39%, 95% CI (35%, 43%)], and more than 1-year follow up [ES = 45%, 95% CI (32%, 58%)]. CONCLUSIONS: Our meta-analysis demonstrated that the mortality of patients with dementia suffered from hip fracture surgery is 12%, 32%, 39%, and 45%, and dementia increased 1.57, 1.97, 1.77, and 1.60-fold mortality in patients undergoing hip fracture surgery in 30-day, 6-month, 1-year, and more than 1-year follow up respectively. BioMed Central 2018-11-23 /pmc/articles/PMC6260652/ /pubmed/30470251 http://dx.doi.org/10.1186/s13018-018-0988-6 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Bai, Jianzhong Zhang, Pei Liang, Xinyu Wu, Zhipeng Wang, Jingcheng Liang, Yuan Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis |
title | Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis |
title_full | Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis |
title_fullStr | Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis |
title_full_unstemmed | Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis |
title_short | Association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis |
title_sort | association between dementia and mortality in the elderly patients undergoing hip fracture surgery: a meta-analysis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260652/ https://www.ncbi.nlm.nih.gov/pubmed/30470251 http://dx.doi.org/10.1186/s13018-018-0988-6 |
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