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Soluble immune checkpoints in cancer: production, function and biological significance

Immune checkpoints play important roles in immune regulation, and blocking immune checkpoints on the cell membrane is a promising strategy in the treatment of cancer. Based on this, monoclonal antibodies are having much rapid development, such as those against CTLA-4 (cytotoxic T lymphocyte antigen...

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Detalles Bibliográficos
Autores principales: Gu, Daqian, Ao, Xiang, Yang, Yu, Chen, Zhuo, Xu, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260693/
https://www.ncbi.nlm.nih.gov/pubmed/30482248
http://dx.doi.org/10.1186/s40425-018-0449-0

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