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Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report

BACKGROUND: Magnetic resonance guided high-intensity focused ultrasound (MR-HIFU) therapy is not feasible in all patients with uterine fibroids because of limiting anatomical factors such as scar tissue, bowel loops or other obstacles in the sonication path. These may prevent the treatment or limit...

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Autores principales: Sainio, Teija, Komar, Gaber, Saunavaara, Jani, Suomi, Visa, Joronen, Kirsi, Perheentupa, Antti, Viitala, Antti, Sequeiros, Roberto Blanco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260726/
https://www.ncbi.nlm.nih.gov/pubmed/30505445
http://dx.doi.org/10.1186/s40349-018-0116-4
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author Sainio, Teija
Komar, Gaber
Saunavaara, Jani
Suomi, Visa
Joronen, Kirsi
Perheentupa, Antti
Viitala, Antti
Sequeiros, Roberto Blanco
author_facet Sainio, Teija
Komar, Gaber
Saunavaara, Jani
Suomi, Visa
Joronen, Kirsi
Perheentupa, Antti
Viitala, Antti
Sequeiros, Roberto Blanco
author_sort Sainio, Teija
collection PubMed
description BACKGROUND: Magnetic resonance guided high-intensity focused ultrasound (MR-HIFU) therapy is not feasible in all patients with uterine fibroids because of limiting anatomical factors such as scar tissue, bowel loops or other obstacles in the sonication path. These may prevent the treatment or limit the treatment window, and therefore, also the volume where HIFU therapy can be delivered. Bowel loops present a particular problem because of bowel gas bubbles and hard particles which may cause reflection or absorption of ultrasound energy, potentially leading to thermal damage and even bowel perforation. Most commonly used techniques for bowel repositioning are bladder and/or rectum filling but these are not always sufficient to reposition the bowel loops. With more efficient bowel repositioning technique, the number of eligible patients for MR-HIFU treatment could be increased, and therapy efficacy be improved in cases where bowel loops limit the treatment window. CASE PRESENTATION: A wedged exterior gel pad was used in two patients presented with in total of four symptomatic fibroids undergoing MR-HIFU treatment when bladder and/or rectum filling was not sufficient to reposition the bowel loops. No severe adverse effects were observed in these cases. The non-perfused volume ratios (NPVs) immediately after treatment were 86% and 39% for the first patient, and 3% for the second patient. CONCLUSIONS: Our preliminary experience suggests that the use of a wedged gel pad during MR-HIFU treatment could be an effective tool to manipulate the bowels in cases where the bladder and/or rectum filling is not sufficient to reposition the bowel loops. A wedged gel pad could also be used in other situations to achieve better treatment coverage to the uterine fibroid.
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spelling pubmed-62607262018-11-30 Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report Sainio, Teija Komar, Gaber Saunavaara, Jani Suomi, Visa Joronen, Kirsi Perheentupa, Antti Viitala, Antti Sequeiros, Roberto Blanco J Ther Ultrasound Case Study BACKGROUND: Magnetic resonance guided high-intensity focused ultrasound (MR-HIFU) therapy is not feasible in all patients with uterine fibroids because of limiting anatomical factors such as scar tissue, bowel loops or other obstacles in the sonication path. These may prevent the treatment or limit the treatment window, and therefore, also the volume where HIFU therapy can be delivered. Bowel loops present a particular problem because of bowel gas bubbles and hard particles which may cause reflection or absorption of ultrasound energy, potentially leading to thermal damage and even bowel perforation. Most commonly used techniques for bowel repositioning are bladder and/or rectum filling but these are not always sufficient to reposition the bowel loops. With more efficient bowel repositioning technique, the number of eligible patients for MR-HIFU treatment could be increased, and therapy efficacy be improved in cases where bowel loops limit the treatment window. CASE PRESENTATION: A wedged exterior gel pad was used in two patients presented with in total of four symptomatic fibroids undergoing MR-HIFU treatment when bladder and/or rectum filling was not sufficient to reposition the bowel loops. No severe adverse effects were observed in these cases. The non-perfused volume ratios (NPVs) immediately after treatment were 86% and 39% for the first patient, and 3% for the second patient. CONCLUSIONS: Our preliminary experience suggests that the use of a wedged gel pad during MR-HIFU treatment could be an effective tool to manipulate the bowels in cases where the bladder and/or rectum filling is not sufficient to reposition the bowel loops. A wedged gel pad could also be used in other situations to achieve better treatment coverage to the uterine fibroid. BioMed Central 2018-11-28 /pmc/articles/PMC6260726/ /pubmed/30505445 http://dx.doi.org/10.1186/s40349-018-0116-4 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Study
Sainio, Teija
Komar, Gaber
Saunavaara, Jani
Suomi, Visa
Joronen, Kirsi
Perheentupa, Antti
Viitala, Antti
Sequeiros, Roberto Blanco
Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report
title Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report
title_full Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report
title_fullStr Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report
title_full_unstemmed Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report
title_short Wedged gel pad for bowel manipulation during MR-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report
title_sort wedged gel pad for bowel manipulation during mr-guided high-intensity focused ultrasound therapy to treat uterine fibroids: a case report
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260726/
https://www.ncbi.nlm.nih.gov/pubmed/30505445
http://dx.doi.org/10.1186/s40349-018-0116-4
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