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Inactivation of DNA repair—prospects for boosting cancer immune surveillance
The emergence of drug resistance depends on the ability of the genome of cancer cells to constantly mutate and evolve under selective pressures. The generation of new mutations is accelerated when genes involved in DNA repair pathways are altered. Notably, although the emergence of new mutations fos...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260742/ https://www.ncbi.nlm.nih.gov/pubmed/30486892 http://dx.doi.org/10.1186/s13073-018-0603-9 |