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Production of a recombinant peroxidase in different glyco-engineered Pichia pastoris strains: a morphological and physiological comparison
BACKGROUND: The methylotrophic yeast Pichia pastoris is a common host for the production of recombinant proteins. However, hypermannosylation hinders the use of recombinant proteins from yeast in most biopharmaceutical applications. Glyco-engineered yeast strains produce more homogeneously glycosyla...
Autores principales: | Pekarsky, Alexander, Veiter, Lukas, Rajamanickam, Vignesh, Herwig, Christoph, Grünwald-Gruber, Clemens, Altmann, Friedrich, Spadiut, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260843/ https://www.ncbi.nlm.nih.gov/pubmed/30474550 http://dx.doi.org/10.1186/s12934-018-1032-6 |
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