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Anti-inflammatory and anti-oxidant mechanisms of an MMP-8 inhibitor in lipoteichoic acid-stimulated rat primary astrocytes: involvement of NF-κB, Nrf2, and PPAR-γ signaling pathways

BACKGROUND: Recent evidence suggests that reactive astrocytes play an important role in neuroinflammation and neurodegenerative diseases. Thus, controlling astrocyte reactivity has been suggested as a promising strategy for treating neurodegenerative diseases. In the present study, we investigated w...

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Detalles Bibliográficos
Autores principales:	Lee, Eun-Jung, Park, Jin-Sun, Lee, Yu-Young, Kim, Do-Yeon, Kang, Jihee Lee, Kim, Hee-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260848/ https://www.ncbi.nlm.nih.gov/pubmed/30470240 http://dx.doi.org/10.1186/s12974-018-1363-6

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