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High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections

BACKGROUND: The host response to intruders in the central nervous system (CNS) may be beneficial but could also be harmful and responsible for neurologic symptoms and sequelae in CNS infections. This immune response induces the activation of the kynurenine pathway (KP) with the production of neuroac...

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Detalles Bibliográficos
Autores principales:	Quist-Paulsen, Else, Aukrust, Pål, Kran, Anne-Marte Bakken, Dunlop, Oona, Ormaasen, Vidar, Stiksrud, Birgitte, Midttun, Øivind, Ueland, Thor, Ueland, Per Magne, Mollnes, Tom Eirik, Dyrhol-Riise, Anne Ma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260858/ https://www.ncbi.nlm.nih.gov/pubmed/30470234 http://dx.doi.org/10.1186/s12974-018-1366-3

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