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HIV-1 immunogens and strategies to drive antibody responses towards neutralization breadth
Despite enormous efforts no HIV-1 vaccine has been developed that elicits broadly neutralizing antibodies (bNAbs) to protect against infection to date. The high antigenic diversity and dense N-linked glycan armor, which covers nearly the entire HIV-1 envelope protein (Env), are major roadblocks for...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260891/ https://www.ncbi.nlm.nih.gov/pubmed/30477581 http://dx.doi.org/10.1186/s12977-018-0457-7 |