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Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts

Cells that had undergone telomere dysfunction‐induced senescence secrete numerous cytokines and other molecules, collectively called the senescence‐associated secretory phenotype (SASP). Although certain SASP factors have been demonstrated to promote cellular senescence in neighboring cells in a par...

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Detalles Bibliográficos
Autores principales: Razdan, Neetu, Vasilopoulos, Themistoklis, Herbig, Utz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260909/
https://www.ncbi.nlm.nih.gov/pubmed/30244523
http://dx.doi.org/10.1111/acel.12838

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