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Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

Hutchinson–Gilford progeria syndrome (HGPS) is a lethal premature aging that recapitulates many normal aging characteristics. This disorder is caused by mutation in the LMNA gene leading to the production of progerin which induces misshapen nuclei, cellular senescence, and aging. We previously showe...

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Detalles Bibliográficos
Autores principales:	Griveau, Audrey, Wiel, Clotilde, Le Calvé, Benjamin, Ziegler, Dorian V., Djebali, Sophia, Warnier, Marine, Martin, Nadine, Marvel, Jacqueline, Vindrieux, David, Bergo, Martin O., Bernard, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260922/ https://www.ncbi.nlm.nih.gov/pubmed/30216637 http://dx.doi.org/10.1111/acel.12835

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