Cargando…

Non-significant p-values? Strategies to understand and better determine the importance of effects and interactions in logistic regression

In the context of generalized linear models (GLMs), interactions are automatically induced on the natural scale of the data. The conventional approach to measuring effects in GLMs based on significance testing (e.g. the Wald test or using deviance to assess model fit) is not always appropriate. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Vakhitova, Zarina I., Alston-Knox, Clair L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261058/
https://www.ncbi.nlm.nih.gov/pubmed/30475804
http://dx.doi.org/10.1371/journal.pone.0205076
_version_ 1783374910966464512
author Vakhitova, Zarina I.
Alston-Knox, Clair L.
author_facet Vakhitova, Zarina I.
Alston-Knox, Clair L.
author_sort Vakhitova, Zarina I.
collection PubMed
description In the context of generalized linear models (GLMs), interactions are automatically induced on the natural scale of the data. The conventional approach to measuring effects in GLMs based on significance testing (e.g. the Wald test or using deviance to assess model fit) is not always appropriate. The objective of this paper is to demonstrate the limitations of these conventional approaches and to explore alternative strategies for determining the importance of effects. The paper compares four approaches to determining the importance of effects in the GLM using 1) the Wald statistic, 2) change in deviance (model fitting criteria), 3) Bayesian GLM using vaguely informative priors and 4) Bayesian Model Averaging analysis. The main points in this paper are illustrated using an example study, which examines the risk factors for cyber abuse victimization, and are further examined using a simulation study. Analysis of our example dataset shows that, in terms of a logistic GLM, the conventional methods using the Wald test and the change in deviance can produce results that are difficult to interpret; Bayesian analysis of GLM is a suitable alternative, which is enhanced with prior knowledge about the direction of the effects; and Bayesian Model Averaging (BMA) is especially suited for new areas of research, particularly in the absence of theory. We recommend that social scientists consider including BMA in their standard toolbox for analysis of GLMs.
format Online
Article
Text
id pubmed-6261058
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-62610582018-12-06 Non-significant p-values? Strategies to understand and better determine the importance of effects and interactions in logistic regression Vakhitova, Zarina I. Alston-Knox, Clair L. PLoS One Research Article In the context of generalized linear models (GLMs), interactions are automatically induced on the natural scale of the data. The conventional approach to measuring effects in GLMs based on significance testing (e.g. the Wald test or using deviance to assess model fit) is not always appropriate. The objective of this paper is to demonstrate the limitations of these conventional approaches and to explore alternative strategies for determining the importance of effects. The paper compares four approaches to determining the importance of effects in the GLM using 1) the Wald statistic, 2) change in deviance (model fitting criteria), 3) Bayesian GLM using vaguely informative priors and 4) Bayesian Model Averaging analysis. The main points in this paper are illustrated using an example study, which examines the risk factors for cyber abuse victimization, and are further examined using a simulation study. Analysis of our example dataset shows that, in terms of a logistic GLM, the conventional methods using the Wald test and the change in deviance can produce results that are difficult to interpret; Bayesian analysis of GLM is a suitable alternative, which is enhanced with prior knowledge about the direction of the effects; and Bayesian Model Averaging (BMA) is especially suited for new areas of research, particularly in the absence of theory. We recommend that social scientists consider including BMA in their standard toolbox for analysis of GLMs. Public Library of Science 2018-11-26 /pmc/articles/PMC6261058/ /pubmed/30475804 http://dx.doi.org/10.1371/journal.pone.0205076 Text en © 2018 Vakhitova, Alston-Knox http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Vakhitova, Zarina I.
Alston-Knox, Clair L.
Non-significant p-values? Strategies to understand and better determine the importance of effects and interactions in logistic regression
title Non-significant p-values? Strategies to understand and better determine the importance of effects and interactions in logistic regression
title_full Non-significant p-values? Strategies to understand and better determine the importance of effects and interactions in logistic regression
title_fullStr Non-significant p-values? Strategies to understand and better determine the importance of effects and interactions in logistic regression
title_full_unstemmed Non-significant p-values? Strategies to understand and better determine the importance of effects and interactions in logistic regression
title_short Non-significant p-values? Strategies to understand and better determine the importance of effects and interactions in logistic regression
title_sort non-significant p-values? strategies to understand and better determine the importance of effects and interactions in logistic regression
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261058/
https://www.ncbi.nlm.nih.gov/pubmed/30475804
http://dx.doi.org/10.1371/journal.pone.0205076
work_keys_str_mv AT vakhitovazarinai nonsignificantpvaluesstrategiestounderstandandbetterdeterminetheimportanceofeffectsandinteractionsinlogisticregression
AT alstonknoxclairl nonsignificantpvaluesstrategiestounderstandandbetterdeterminetheimportanceofeffectsandinteractionsinlogisticregression