Cargando…
Transgenic zebrafish models reveal distinct molecular mechanisms for cataract-linked αA-crystallin mutants
Mutations in the small heat shock proteins α-crystallins have been linked to autosomal dominant cataracts in humans. Extensive studies in vitro have revealed a spectrum of alterations to the structure and function of these proteins including shifts in the size of the oligomer, modulation of subunit...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261105/ https://www.ncbi.nlm.nih.gov/pubmed/30475834 http://dx.doi.org/10.1371/journal.pone.0207540 |