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Structural basis for σ(1) receptor ligand recognition

The σ(1) receptor is a poorly understood membrane protein expressed throughout the human body. Ligands targeting the σ(1) receptor are in clinical trials for treatment of Alzheimer’s disease, ischemic stroke, and neuropathic pain. Despite this, relatively little is known regarding the σ(1) receptor’...

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Detalles Bibliográficos
Autores principales:	Schmidt, Hayden R., Betz, Robin M., Dror, Ron O., Kruse, Andrew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261271/ https://www.ncbi.nlm.nih.gov/pubmed/30291362 http://dx.doi.org/10.1038/s41594-018-0137-2

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