Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration

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Physicians have observed that surgical wounds in the elderly heal with thinner scars than wounds in young patients. Understanding this phenomenon may reveal strategies for promoting scarless wound repair. We show that full-thickness skin wounds in aged but not young mice fully regenerate. Exposure o...

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Detalles Bibliográficos
Autores principales: Nishiguchi, Mailyn A., Spencer, Casey A., Leung, Denis H., Leung, Thomas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261459/
https://www.ncbi.nlm.nih.gov/pubmed/30257200
http://dx.doi.org/10.1016/j.celrep.2018.08.054
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