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Mitochondrial dysfunction as a mechanism of drug-induced hepatotoxicity: current understanding and future perspectives

Mitochondria are critical cellular organelles for energy generation and are now also recognized as playing important roles in cellular signaling. Their central role in energy metabolism, as well as their high abundance in hepatocytes, make them important targets for drug-induced hepatotoxicity. This...

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Detalles Bibliográficos
Autores principales: Ramachandran, Anup, Visschers, Ruben G.J., Duan, Luqi, Akakpo, Jephte Y., Jaeschke, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Whioce Publishing Pte. Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261533/
https://www.ncbi.nlm.nih.gov/pubmed/30873497