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Mitochondrial dysfunction as a mechanism of drug-induced hepatotoxicity: current understanding and future perspectives
Mitochondria are critical cellular organelles for energy generation and are now also recognized as playing important roles in cellular signaling. Their central role in energy metabolism, as well as their high abundance in hepatocytes, make them important targets for drug-induced hepatotoxicity. This...
Autores principales: | Ramachandran, Anup, Visschers, Ruben G.J., Duan, Luqi, Akakpo, Jephte Y., Jaeschke, Hartmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Whioce Publishing Pte. Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261533/ https://www.ncbi.nlm.nih.gov/pubmed/30873497 |
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