Conditional mutagenesis by oligonucleotide-mediated integration of loxP sites in zebrafish

Many eukaryotic genes play essential roles in multiple biological processes in several different tissues. Conditional mutants are needed to analyze genes with such pleiotropic functions. In vertebrates, conditional gene inactivation has only been feasible in the mouse, leaving other model systems to...

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Detalles Bibliográficos
Autores principales: Burg, Leonard, Palmer, Nicholas, Kikhi, Khrievono, Miroshnik, Evgeniya S., Rueckert, Helen, Gaddy, Eleanor, MacPherson Cunningham, Carlee, Mattonet, Kenny, Lai, Shih-Lei, Marín-Juez, Rubén, Waring, Richard B., Stainier, Didier Y. R., Balciunas, Darius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261631/
https://www.ncbi.nlm.nih.gov/pubmed/30427827
http://dx.doi.org/10.1371/journal.pgen.1007754

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