Intramembrane ionic protein–lipid interaction regulates integrin structure and function

Protein transmembrane domains (TMDs) are generally hydrophobic, but our bioinformatics analysis shows that many TMDs contain basic residues at terminal regions. Physiological functions of these membrane-snorkeling basic residues are largely unclear. Here, we show that a membrane-snorkeling Lys resid...

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Detalles Bibliográficos
Autores principales: Guo, Jun, Zhang, Youhua, Li, Hua, Chu, Huiying, Wang, Qinshu, Jiang, Shutan, Li, Yan, Shen, Hongbin, Li, Guohui, Chen, Jianfeng, Xu, Chenqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261646/
https://www.ncbi.nlm.nih.gov/pubmed/30427828
http://dx.doi.org/10.1371/journal.pbio.2006525

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