A comparison of biological activity of commercially available purified native botulinum neurotoxin serotypes A1 to F1 in vitro, ex vivo, and in vivo

Botulinum neurotoxin (BoNT) is a major therapeutic agent. Of seven native BoNT serotypes (A to G), only A and B are currently used in the clinic. Here we compared the potency of commercially available purified native serotypes A1 to F1 across in vitro, ex vivo, and in vivo assays. BoNT potency in vi...

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Detalles Bibliográficos
Autores principales: Donald, Sarah, Elliott, Mark, Gray, Bryony, Hornby, Fraser, Lewandowska, Agnieszka, Marlin, Sandra, Favre‐Guilmard, Christine, Périer, Cindy, Cornet, Sylvie, Kalinichev, Mikhail, Krupp, Johannes, Fonfria, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261930/
https://www.ncbi.nlm.nih.gov/pubmed/30519475
http://dx.doi.org/10.1002/prp2.446

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