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Interaction paths promote module integration and network-level robustness of spliceosome to cascading effects
The functionality of distinct types of protein networks depends on the patterns of protein-protein interactions. A problem to solve is understanding the fragility of protein networks to predict system malfunctioning due to mutations and other errors. Spectral graph theory provides tools to understan...
Autores principales: | Guimarães, Paulo R., Pires, Mathias M., Cantor, Maurício, Coltri, Patricia P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261937/ https://www.ncbi.nlm.nih.gov/pubmed/30487551 http://dx.doi.org/10.1038/s41598-018-35160-6 |
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