Enhanced breast cancer progression by mutant p53 is inhibited by the circular RNA circ-Ccnb1

TP53 mutations occur in many different types of cancers that produce mutant p53 proteins. The mutant p53 proteins have lost wild-type p53 activity and gained new functions that contribute to malignant tumor progression. Different p53 mutations create distinct profiles in loss of wild-type p53 activi...

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Detalles Bibliográficos
Autores principales: Fang, Ling, Du, William W., Lyu, Juanjuan, Dong, Jun, Zhang, Chao, Yang, Weining, He, Alina, Kwok, Yat Sze Sheila, Ma, Jian, Wu, Nan, Li, Feiya, Awan, Faryal Mehwish, He, Chengyan, Yang, Bing L., Peng, Chun, MacKay, Helen J., Yee, Albert J., Yang, Burton B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261950/
https://www.ncbi.nlm.nih.gov/pubmed/29795334
http://dx.doi.org/10.1038/s41418-018-0115-6

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