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Prevention of neuronal apoptosis by astrocytes through thiol-mediated stress response modulation and accelerated recovery from proteotoxic stress
The development of drugs directly interfering with neurodegeneration has proven to be astonishingly difficult. Alternative therapeutic approaches could result from a better understanding of the supportive function of glial cells for stressed neurons. Therefore, here, we investigated the mechanisms i...
Autores principales: | Gutbier, Simon, Spreng, Anna-Sophie, Delp, Johannes, Schildknecht, Stefan, Karreman, Christiaan, Suciu, Ilinca, Brunner, Thomas, Groettrup, Marcus, Leist, Marcel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261954/ https://www.ncbi.nlm.nih.gov/pubmed/30390092 http://dx.doi.org/10.1038/s41418-018-0229-x |
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