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Dynamic interaction of poly(A)-binding protein with the ribosome

Eukaryotic mRNA has a cap structure and a poly(A) tail at the 5′ and 3′ ends, respectively. The cap structure is recognized by eIF (eukaryotic translation initiation factor) 4 F, while the poly(A) tail is bound by poly(A)-binding protein (PABP). PABP has four RNA recognition motifs (RRM1–4), and RRM...

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Detalles Bibliográficos
Autores principales: Machida, Kodai, Shigeta, Tomoaki, Yamamoto, Yuki, Ito, Takuhiro, Svitkin, Yuri, Sonenberg, Nahum, Imataka, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261967/
https://www.ncbi.nlm.nih.gov/pubmed/30487538
http://dx.doi.org/10.1038/s41598-018-35753-1