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Dynamic interaction of poly(A)-binding protein with the ribosome
Eukaryotic mRNA has a cap structure and a poly(A) tail at the 5′ and 3′ ends, respectively. The cap structure is recognized by eIF (eukaryotic translation initiation factor) 4 F, while the poly(A) tail is bound by poly(A)-binding protein (PABP). PABP has four RNA recognition motifs (RRM1–4), and RRM...
Autores principales: | Machida, Kodai, Shigeta, Tomoaki, Yamamoto, Yuki, Ito, Takuhiro, Svitkin, Yuri, Sonenberg, Nahum, Imataka, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261967/ https://www.ncbi.nlm.nih.gov/pubmed/30487538 http://dx.doi.org/10.1038/s41598-018-35753-1 |
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