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Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress
Reduced choroidal blood flow and tissue changes in the ageing human eye impair oxygen delivery to photoreceptors and the retinal pigment epithelium. As a consequence, mild but chronic hypoxia may develop and disturb cell metabolism, function and ultimately survival, potentially contributing to retin...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261999/ https://www.ncbi.nlm.nih.gov/pubmed/29666476 http://dx.doi.org/10.1038/s41418-018-0094-7 |