Cargando…

Chronic Sleep Disruption Advances the Temporal Progression of Tauopathy in P301S Mutant Mice

Brainstem locus ceruleus neurons (LCn) are among the first neurons across the lifespan to evidence tau pathology, and LCn are implicated in tau propagation throughout the cortices. Yet, events influencing LCn tau are poorly understood. Activated persistently across wakefulness, LCn experience signif...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Yan, Zhan, Guanxia, Fenik, Polina, Brandes, Madison, Bell, Patrick, Francois, Noelle, Shulman, Katherine, Veasey, Sigrid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262148/ https://www.ncbi.nlm.nih.gov/pubmed/30322903 http://dx.doi.org/10.1523/JNEUROSCI.0275-18.2018

Ejemplares similares

Degeneration in Arousal Neurons in Chronic Sleep Disruption Modeling Sleep Apnea
por: Zhu, Yan, et al.
Publicado: (2015)

Late-in-life neurodegeneration after chronic sleep loss in young adult mice
por: Owen, Jessica E, et al.
Publicado: (2021)

Hypocretin/orexin influences chronic sleep disruption injury in the hippocampus
por: Nick, Henry, et al.
Publicado: (2022)

Tauopathy-induced retinal dysfunction in the P301S mutant human tau transgenic mouse
por: Mazzaro, Nadia, et al.
Publicado: (2013)

Dysfunction of the glutamatergic photoreceptor synapse in the P301S mouse model of tauopathy
por: Arouche-Delaperche, L., et al.
Publicado: (2023)

P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating
por: Takeuchi, Hiroki, et al.
Publicado: (2011)

Editorial: Roles of Sleep Disruption and Circadian Rhythm Alterations on Neurodegeneration and Alzheimer's Disease
por: Duncan, Marilyn J., et al.
Publicado: (2021)

p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model
por: Perea, Juan R., et al.
Publicado: (2022)

Progressive tauopathy disrupts breathing stability and chemoreflexes during presumptive sleep in mice
por: Marciante, Alexandria B., et al.
Publicado: (2023)

Organotypic Brain Slice Cultures of Adult Transgenic P301S Mice—A Model for Tauopathy Studies
por: Mewes, Agneta, et al.
Publicado: (2012)

SWI and phase imaging reveal intracranial calcifications in the P301L mouse model of human tauopathy
por: Ni, Ruiqing, et al.
Publicado: (2020)

Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy
por: Williams, Tristan, et al.
Publicado: (2023)

An X on the Map for Sleep Apnea’s Holy Grail: Drug Therapy
por: Veasey, Sigrid
Publicado: (2021)

Glimepiride mitigates tauopathy and neuroinflammation in P301S transgenic mice: role of AKT/GSK3β signaling
por: Zaki, Mennatallah O., et al.
Publicado: (2022)

α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice
por: Zhang, Yan-Hui, et al.
Publicado: (2017)

Piecing Together Phenotypes of Brain Injury and Dysfunction in Obstructive Sleep Apnea
por: Veasey, Sigrid C.
Publicado: (2012)

Phospho-Tau Accumulation and Structural Alterations of the Golgi Apparatus of Cortical Pyramidal Neurons in the P301S Tauopathy Mouse Model
por: Antón-Fernández, Alejandro, et al.
Publicado: (2017)

Behavioural Functions and Cerebral Blood Flow in a P301S Tauopathy Mouse Model: A Time-Course Study
por: Ahmad, Faraz, et al.
Publicado: (2021)

Arterial spin labeling demonstrates preserved regional cerebral blood flow in the P301L mouse model of tauopathy
por: Kindler, Diana, et al.
Publicado: (2021)

Mu-opioid receptor-expressing neurons in the paraventricular thalamus modulate chronic morphine-induced wake alterations
por: Eacret, Darrell, et al.
Publicado: (2023)

Making Sense of Oxidative Stress in Obstructive Sleep Apnea: Mediator or Distracter?
por: Zhang, Jing, et al.
Publicado: (2012)

Bidirectional Relationship between Opioids and Disrupted Sleep: Putative Mechanisms
por: Eacret, D., et al.
Publicado: (2020)

Altered Brain Arginine Metabolism and Polyamine System in a P301S Tauopathy Mouse Model: A Time-Course Study
por: Mein, Hannah, et al.
Publicado: (2022)

Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy
por: Theunis, Clara, et al.
Publicado: (2013)

TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits12
por: Wang, Hongjie, et al.
Publicado: (2016)

Structural MRI Reveals Cervical Spinal Cord Atrophy in the P301L Mouse Model of Tauopathy: Gender and Transgene-Dosing Effects
por: Sartoretti, Thomas, et al.
Publicado: (2022)

Effects of Low-Intensity Pulsed Ultrasound-Induced Blood–Brain Barrier Opening in P301S Mice Modeling Alzheimer’s Disease Tauopathies
por: Géraudie, Amandine, et al.
Publicado: (2023)

Plasticity in visual cortex is disrupted in a mouse model of tauopathy
por: Papanikolaou, Amalia, et al.
Publicado: (2022)

A Novel Triple Repeat Mutant Tau Transgenic Model That Mimics Aspects of Pick’s Disease and Fronto-Temporal Tauopathies
por: Rockenstein, Edward, et al.
Publicado: (2015)

Neural Consequences of Chronic Short Sleep: Reversible or Lasting?
por: Zhao, Zhengqing, et al.
Publicado: (2017)

Mutant β(1)-adrenergic receptor improves REM sleep and ameliorates tau accumulation in a mouse model of tauopathy
por: Dong, Qing, et al.
Publicado: (2023)

Diffusion Tensor Imaging Detects Acute Pathology-Specific Changes in the P301L Tauopathy Mouse Model Following Traumatic Brain Injury
por: Soni, Neha, et al.
Publicado: (2021)

Temporal Variant Frontotemporal Dementia Is Associated with Globular Glial Tauopathy
por: Clark, Camilla N., et al.
Publicado: (2015)

Small-molecule modulation of the p75 neurotrophin receptor inhibits a wide range of tau molecular pathologies and their sequelae in P301S tauopathy mice
por: Yang, Tao, et al.
Publicado: (2020)

Pneumonia initiates a tauopathy
por: Balczon, Ron, et al.
Publicado: (2021)

S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy
por: Amal, Haitham, et al.
Publicado: (2019)

Small molecule inhibitor of tau self-association in a mouse model of tauopathy: A preventive study in P301L tau JNPL3 mice
por: Davidowitz, Eliot J., et al.
Publicado: (2023)

Tau Causes Synapse Loss without Disrupting Calcium Homeostasis in the rTg4510 Model of Tauopathy
por: Kopeikina, Katherine J., et al.
Publicado: (2013)

In vivo functional brain mapping in a conditional mouse model of human tauopathy (tau(p301l)) reveals reduced neural activity in memory formation structures
por: Perez, Pablo D, et al.
Publicado: (2013)

Astrocytes in Tauopathies
por: Reid, Matthew J., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2seuodnd4m168ecifsrtrdn2s8