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Regulating Innate and Adaptive Immunity for Controlling SIV Infection by 25-Hydroxycholesterol

Persistent inflammation and extensive immune activation have been associated with HIV-1/SIV pathogenesis. Previously, we reported that cholesterol-25-hydroxylase (CH25H) and its metabolite 25-hydroxycholesterol (25-HC) had a broad antiviral activity in inhibiting Zika, Ebola, and HIV-1 infection. Ho...

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Detalles Bibliográficos
Autores principales:	Wu, Tongjin, Ma, Feng, Ma, Xiuchang, Jia, Weizhe, Pan, Enxiang, Cheng, Genhong, Chen, Ling, Sun, Caijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262225/ https://www.ncbi.nlm.nih.gov/pubmed/30524435 http://dx.doi.org/10.3389/fimmu.2018.02686

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