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An integrative machine learning approach for prediction of toxicity-related drug safety

Recent trends in drug development have been marked by diminishing returns caused by the escalating costs and falling rates of new drug approval. Unacceptable drug toxicity is a substantial cause of drug failure during clinical trials and the leading cause of drug withdraws after release to the marke...

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Detalles Bibliográficos
Autores principales: Lysenko, Artem, Sharma, Alok, Boroevich, Keith A, Tsunoda, Tatsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262234/
https://www.ncbi.nlm.nih.gov/pubmed/30515477
http://dx.doi.org/10.26508/lsa.201800098