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An integrative machine learning approach for prediction of toxicity-related drug safety
Recent trends in drug development have been marked by diminishing returns caused by the escalating costs and falling rates of new drug approval. Unacceptable drug toxicity is a substantial cause of drug failure during clinical trials and the leading cause of drug withdraws after release to the marke...
Autores principales: | Lysenko, Artem, Sharma, Alok, Boroevich, Keith A, Tsunoda, Tatsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262234/ https://www.ncbi.nlm.nih.gov/pubmed/30515477 http://dx.doi.org/10.26508/lsa.201800098 |
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