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Development of a novel rat model of heterogeneous hepatic injury by injection with colchicine via the splenic vein

AIM: To develop a novel rat model of heterogeneous hepatic injury. METHODS: Seventy male Sprague-Dawley rats were randomly divided into a control group (n = 10) and a colchicine group (n = 60). A 0.25% colchicine solution (0.4 mL/kg) was injected via the splenic vein in the colchicine group to devel...

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Detalles Bibliográficos
Autores principales: Zhang, Yan-Yan, Zhang, Chao-Xu, Li, Yu, Jiang, Xuan, Wang, Yong-Fang, Sun, Yang, Wang, Jun, Ji, Wan-Ying, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262251/
https://www.ncbi.nlm.nih.gov/pubmed/30510375
http://dx.doi.org/10.3748/wjg.v24.i44.5005