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Inhibiting the NLRP3 Inflammasome With MCC950 Ameliorates Isoflurane-Induced Pyroptosis and Cognitive Impairment in Aged Mice

Nod-like receptor protein 3 (NLRP3) inflammasome activation has been implicated in the pathogenesis of general anesthesia (GA)-induced neuroinflammation and cognitive impairment in aged rodents. However, the cellular basis for cognitive impairment is still not fully understood, and effective pharmac...

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Detalles Bibliográficos
Autores principales:	Fan, Yunxia, Du, Liwu, Fu, Qun, Zhou, Zhiqiang, Zhang, Jingyu, Li, Guomin, Wu, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262296/ https://www.ncbi.nlm.nih.gov/pubmed/30524241 http://dx.doi.org/10.3389/fncel.2018.00426

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