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Targeted Mutation (R100W) of the Gene Encoding NGF Leads to Deficits in the Peripheral Sensory Nervous System

Nerve growth factor (NGF) exerts multifaceted functions through different stages of life. A missense mutation (R100W) in the beta-NGF gene was found in hereditary sensory autonomic neuropathy V (HSAN V) patients with severe loss of pain perception but without overt cognitive impairment. To better un...

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Detalles Bibliográficos
Autores principales:	Yang, Wanlin, Sung, Kijung, Zhou, Fengli, Xu, Wei, Rissman, Robert A., Ding, Jianqing, Wu, Chengbiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262302/ https://www.ncbi.nlm.nih.gov/pubmed/30524266 http://dx.doi.org/10.3389/fnagi.2018.00373

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