Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives

Microtubules are tubulin polymer structures, which are indispensable for cell growth and division. Its constituent protein β-tubulin has been a common drug target for various diseases including cancer. Colchicine has been used to treat gout, but it has also been an investigational anticancer agent w...

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Detalles Bibliográficos
Autores principales: Majcher, Urszula, Klejborowska, Greta, Moshari, Mahshad, Maj, Ewa, Wietrzyk, Joanna, Bartl, Franz, Tuszynski, Jack A., Huczyński, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262536/
https://www.ncbi.nlm.nih.gov/pubmed/30388878
http://dx.doi.org/10.3390/cells7110192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262536/
https://www.ncbi.nlm.nih.gov/pubmed/30388878
http://dx.doi.org/10.3390/cells7110192

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