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Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives

Microtubules are tubulin polymer structures, which are indispensable for cell growth and division. Its constituent protein β-tubulin has been a common drug target for various diseases including cancer. Colchicine has been used to treat gout, but it has also been an investigational anticancer agent w...

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Detalles Bibliográficos
Autores principales:	Majcher, Urszula, Klejborowska, Greta, Moshari, Mahshad, Maj, Ewa, Wietrzyk, Joanna, Bartl, Franz, Tuszynski, Jack A., Huczyński, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262536/ https://www.ncbi.nlm.nih.gov/pubmed/30388878 http://dx.doi.org/10.3390/cells7110192

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