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Development of an FVIII Inhibitor in a Mild Hemophilia Patient with a Phe595Cys Mutation
Mild hemophilia A is caused by a missense mutation in the FVIII gene that is responsible for a decrease in the FVIII:C to between 5% and 40%. The development of FVIII inhibitors has been reported in 3-13% of patients with mild hemophilia. Genetic risk factors for the development of inhibitors in mil...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Japanese Society of Internal Medicine
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262709/ https://www.ncbi.nlm.nih.gov/pubmed/29877292 http://dx.doi.org/10.2169/internalmedicine.1145-18 |