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Ceritinib Treatment for Carcinomatous Meningitis with a Secondary Mutation at I1171T in Anaplastic Lymphoma Kinase

The mechanisms underlying anaplastic lymphoma kinase (ALK) resistance have not been well investigated in clinical practice. We herein report the case of a lung cancer patient with carcinomatous meningitis who had an ALK I1171T resistance mutation revealed by direct DNA sequencing of the cerebrospina...

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Detalles Bibliográficos
Autores principales: Ashinuma, Hironori, Shingyoji, Masato, Hasegawa, Yuzo, Yokoi, Sana, Yoshida, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262718/
https://www.ncbi.nlm.nih.gov/pubmed/29877262
http://dx.doi.org/10.2169/internalmedicine.0397-17

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