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Necroptosis occurs in osteoblasts during tumor necrosis factor-α stimulation and caspase-8 inhibition

Necroptosis is a regulated cell death mechanism. However, it is unknown whether necroptosis is involved in the death of tumor necrosis factor-α (TNF-α)-treated osteoblasts. Therefore, we conducted the study with TNF-α, Nec-1 (a specific inhibitor of necroptosis), and Z-IETD-FMK (a specific inhibitor...

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Detalles Bibliográficos
Autores principales: Shi, Guan, Jia, Pu, Chen, Hao, Bao, Li, Feng, Fei, Tang, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262749/
https://www.ncbi.nlm.nih.gov/pubmed/30484493
http://dx.doi.org/10.1590/1414-431X20187844