Drosophila melanogaster as a function-based high-throughput screening model for antinephrolithiasis agents in kidney stone patients

Kidney stone disease involves the aggregation of stone-forming salts consequent to solute supersaturation in urine. The development of novel therapeutic agents for this predominantly metabolic and biochemical disorder have been hampered by the lack of a practical pre-clinical model amenable to drug...

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Detalles Bibliográficos
Autores principales: Ali, Sohrab N., Dayarathna, Thamara K., Ali, Aymon N., Osumah, Tijani, Ahmed, Mohamed, Cooper, Tyler T., Power, Nicholas E., Zhang, Dongxing, Kim, Dajung, Kim, Rachel, St. Amant, Andre, Hou, Jinqiang, Tailly, Thomas, Yang, Jun, Luyt, Len, Spagnuolo, Paul A., Burton, Jeremy P., Razvi, Hassan, Leong, Hon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262805/
https://www.ncbi.nlm.nih.gov/pubmed/30082495
http://dx.doi.org/10.1242/dmm.035873

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