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Modelling brain dopamine-serotonin vesicular transport disease in Caenorhabditis elegans

Brain dopamine-serotonin vesicular transport disease is a rare disease caused by autosomal recessive mutations in the SLC18A2 gene, which encodes the VMAT2 protein. VMAT2 is a membrane protein responsible for vesicular transport of monoamines, and its disruption negatively affects neurotransmission....

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Detalles Bibliográficos
Autores principales: Young, Alexander T., Ly, Kien N., Wilson, Callum, Lehnert, Klaus, Snell, Russell G., Reid, Suzanne J., Jacobsen, Jessie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262812/
https://www.ncbi.nlm.nih.gov/pubmed/30266839
http://dx.doi.org/10.1242/dmm.035709

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