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Targeting ulcerative colitis by suppressing glucose uptake with ritonavir

Glucose is the preferred source of energy in activated inflammatory cells. Glucose uptake into the cell is ensured by a family of glucose uptake transporters (GLUTs), which have been identified as off-target molecules of the HIV protease inhibitor ritonavir. In this study, we examined the effect of...

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Detalles Bibliográficos
Autores principales: Jodeleit, Henrika, Al-Amodi, Omar, Caesar, Janina, Villarroel Aguilera, Christina, Holdt, Lesca, Gropp, Roswitha, Beigel, Florian, Siebeck, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262818/
https://www.ncbi.nlm.nih.gov/pubmed/30322872
http://dx.doi.org/10.1242/dmm.036210