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Targeting ulcerative colitis by suppressing glucose uptake with ritonavir
Glucose is the preferred source of energy in activated inflammatory cells. Glucose uptake into the cell is ensured by a family of glucose uptake transporters (GLUTs), which have been identified as off-target molecules of the HIV protease inhibitor ritonavir. In this study, we examined the effect of...
Autores principales: | Jodeleit, Henrika, Al-Amodi, Omar, Caesar, Janina, Villarroel Aguilera, Christina, Holdt, Lesca, Gropp, Roswitha, Beigel, Florian, Siebeck, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262818/ https://www.ncbi.nlm.nih.gov/pubmed/30322872 http://dx.doi.org/10.1242/dmm.036210 |
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