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PWP1 promotes nutrient-responsive expression of 5S ribosomal RNA
PWP1 is a chromatin binding protein with an important role in animal growth control downstream of mTOR-mediated nutrient sensing. PWP1 has been shown to control tissue growth by promoting the transcription of 5.8S, 18S and 28S ribosomal RNAs (rRNAs) by RNA polymerase I (Pol I). Concomitantly with Po...
Autores principales: | Liu, Ying, Cerejeira Matos, Rita, Heino, Tapio I., Hietakangas, Ville |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262851/ https://www.ncbi.nlm.nih.gov/pubmed/30361412 http://dx.doi.org/10.1242/bio.037911 |
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