Cargando…
The mechanistic insight of a specific interaction between 15d-Prostaglandin-J2 and eIF4A suggests an evolutionary conserved role across species
15-deoxy-delta 12,14-prostaglandin J2 (15d-PGJ2) is an anti-inflammatory/anti-neoplastic prostaglandin that functions through covalent binding to cysteine residues of various target proteins. We previously showed that 15d-PGJ2 mediated anti-inflammatory responses are dependent on the translational i...
Autores principales: | Yun, So Jeong, Kim, Hyunjoon, Jung, Seung-Hyun, Kim, Joon Hyun, Ryu, Jeong Eun, Singh, N. Jiten, Jeon, Jouhyun, Han, Jin-Kwan, Kim, Cheol-Hee, Kim, Sanguk, Jang, Sung Key, Kim, Woo Jae |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262856/ https://www.ncbi.nlm.nih.gov/pubmed/30257829 http://dx.doi.org/10.1242/bio.035402 |
Ejemplares similares
-
Integration of Evolutionary Features for the Identification of Functionally Important Residues in Major Facilitator Superfamily Transporters
por: Jeon, Jouhyun, et al.
Publicado: (2009) -
ConPlex: a server for the evolutionary conservation analysis of protein complex structures
por: Choi, Yoon Sup, et al.
Publicado: (2010) -
Network Clustering Revealed the Systemic Alterations of Mitochondrial Protein Expression
por: Jeon, Jouhyun, et al.
Publicado: (2011) -
Spatial and functional organization of mitochondrial protein network
por: Yang, Jae-Seong, et al.
Publicado: (2013) -
eIF2A, an initiator tRNA carrier refractory to eIF2α kinases, functions synergistically with eIF5B
por: Kim, Eunah, et al.
Publicado: (2018)