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Plag1 and Plagl2 have overlapping and distinct functions in telencephalic development
The Plag gene family has three members; Plagl1/Zac1, which is a tumor suppressor gene, and Plag1 and Plagl2, which are proto-oncogenes. All three genes are known to be expressed in embryonic neural progenitors, and Zac1 regulates proliferation, neuronal differentiation and migration in the developin...
Autores principales: | Adnani, Lata, Dixit, Rajiv, Chen, Xingyu, Balakrishnan, Anjali, Modi, Harshil, Touahri, Yacine, Logan, Cairine, Schuurmans, Carol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262857/ https://www.ncbi.nlm.nih.gov/pubmed/30361413 http://dx.doi.org/10.1242/bio.038661 |
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